Intracellular Calcium Dynamics and Anisotropic Reentry in Isolated Canine Pulmonary Veins and Left Atrium
نویسندگان
چکیده
منابع مشابه
Intracellular calcium dynamics and anisotropic reentry in isolated canine pulmonary veins and left atrium.
BACKGROUND Rapid activations due to either focal discharge or reentry are often present during atrial fibrillation (AF) in the pulmonary veins (PVs). The mechanisms of these rapid activations are unclear. METHODS AND RESULTS We studied 7 isolated, Langendorff-perfused canine left atrial (LA) and PV preparations and used 2 cameras to map membrane potential alone (Vm, n=3) or Vm and intracellul...
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OBJECTIVE Left atrium (LA) and left atrial pulmonary venous anatomy have clinical importance for atrial fibrillation (AF) and cardiac tumor surgery. A detailed anatomic knowledge of these structures may faciliate clinical evaluations. The aim of this study was to assess LA size and to demonstrate other anatomic features of LA with pulmonary vein openings in normal population. METHODS This des...
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BACKGROUND The extent of ostial ablation necessary to electrically disconnect the pulmonary vein (PV) myocardial extensions that initiate atrial fibrillation from the left atrium has not been determined. METHODS AND RESULTS Seventy patients underwent PV mapping with a circumferential 10-electrode catheter during sinus rhythm or left atrial pacing. After assessment of perimetric distribution a...
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Ibutilide can prolong refractory period and terminate reentry. Whether ibutilide has the same effects on pulmonary vein (PV) focal discharge (FD) is unclear. We induced sustained atrial fibrillation (AF) in seven dogs by rapid left atrial (LA) pacing for 74 +/- 46 days. Ibutilide was repeatedly infused until it terminated AF (0.02 +/- 0.01 mg/kg) or when a cumulative dose was reached (0.04 mg/k...
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Background Late gadolinium enhanced (LGE) MRI enables scar assessment in the left atrial (LA) wall, providing valuable information for treatment planning and image based procedure guidance in patient with atrial fibrillation (AF). Accurate and objective segmentation of the anatomy of the LA and pulmonary veins (PV) is an important prerequisite for atrial scar assessment. However, segmentation o...
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ژورنال
عنوان ژورنال: Circulation
سال: 2005
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.104.498758